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MLPA

MLPA is a semi-quantitative technique used to detect copy number variation associated with a disease. It was developed as a proprietary technology by MRC Holland for the detection of copy number variations which is considered the gold standard in this field and now being used all over the world to study tumours and hereditary disorders. MLPA (Multiplex Ligation-dependant Probe Amplification (MLPA) is a multiplex PCR based technology that enables the copy number variation (CV) detection of up to 60 DNA sequences in a single reaction. 96 DNA samples can be processed contemporaneously with results being available within 24 hours. Over 350 assays targeting various genetic diseases are available.

MLPA
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BCR ABL Qualitative RT-PCR Kit – Major, Minor, Micro

Single-Tube, Multiplex Real-Time PCR Assay for sensitive and specific detection of Major (M-BCR) p210, Minor (m-BCR) p190, and Micro (μ-BCR) p230 BCR-ABL transcripts.

Applications & Specialities, Infectious Diseases, MLPA, olympus microscope, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, NeoDx, Clinical Diagnostics

BCR ABL Quantitative RT-PCR Kit – Major

IS quantitative, one-step RT-PCR for quantifying the IS ratios of BCR-ABL Major (M-BCR) p210 transcript in CML patient samples.

Applications & Specialities, Cancer Diagnostics Kit, Early cancer detection, Infectious Diseases, MLPA, olympus microscope, Pathology Lab Equipments, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, NeoDx, Clinical Diagnostics

BCR ABL Quantitative RT-PCR Kit – Major, Minor, Micro

Evaluates the molecular response up to 5 log reduction which is undetectable BCR-ABL1.

Applications & Specialities, Cancer Diagnostics Kit, Early cancer detection, Infectious Diseases, MLPA, olympus microscope, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, NeoDx, Clinical Diagnostics

D001 Hereditary Cancer Panel

SALSA® digital Multiplex Ligation-dependent Probe Amplification (digitalMLPA) is a multiplex PCR followed by Illumina sequencing-based amplicon quantification, for the detection of copy number variations (CNV) and specific point mutations. 

Applications & Specialities, Cancer Diagnostics, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND

HLA B27 RT-PCR Detection Kit

Human Leukocyte Antigen B27 (HLA B27) RT-PCR Detection Kit for Exon 2/ Exon 3
for the detection of HLA-B27 allele related to ankylosing spondylitis through real-time PCR, using DNA extracted from Whole Blood, Plasma, or Serum with cyp17a1 as Internal Control.

Applications & Specialities, Early cancer detection, ihc detection kit, Infectious Diseases, MLPA, olympus microscope, Pathology Lab Equipments, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, RT-PCR (Autoimmune), NeoDx, Clinical Diagnostics

JAK2 V617F Mutation Detection Kit

JAK2 V617F Mutation Detection RT-PCR Kit for sensitive and specific detection of JAK2 (Janus Kinase 2) V617F allele in DNA samples with Beta Actin as an internal control.

Applications & Specialities, Cancer Diagnostics Kit, Early cancer detection, Infectious Diseases, MLPA, olympus microscope, Pathology Lab Equipments, Precision Medicine, Real Time PCR, RT-PCR, RT-PCR, NeoDx, Clinical Diagnostics

Methylation-Specific MLPA Assays

Methylation-Specific (MS)-MLPA® is a variant of the MLPA technique, the gold standard in copy number determination. With MS-MLPA, it is possible to semi-quantitatively profile methylation for multiple targets simultaneously.

Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics

MLPA Assays for Lung Disorders

MLPA Assays are useful in finding out those who have Lung Disorders

Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics

MLPA Assays for Cardiovascular Disorders

MLPA can be used for the detection of deletions or duplications of certain genes involved in cardiovascular diseases.

Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics

MLPA Assays for Endocrinological Disorders

MLPA Assays are useful in finding out those who have endocrinological diseases.

Applications & Specialities, MLPA, MLPA, MRC HOLLAND, Clinical Diagnostics

MLPA Assays for Hereditary Blood Disorders

MLPA Assays are useful in finding out those who have hereditary blood disorders.

Applications & Specialities, Congenital & Hereditary Disorders, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics

MLPA Assays for Intellectual Disability

MLPA Assays are useful in finding out those who have Intellectual Disability

Applications & Specialities, Genetic Disorders, Intellectual Disability, Intellectual property, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics

MLPA Assays for Neuromuscular Disorders

MLPA Assays are useful in finding out those who have Neuromuscular Disorders

Applications & Specialities, MLPA, MLPA, MRC HOLLAND, Clinical Diagnostics

MLPA Assays for Skeletal & Connective Tissue

MLPA Assays are useful in finding out those who have Skeletal & Connective Tissue Disorders

Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND

MLPA Assays for Tumour Profiling

MLPA Assays are useful in tumor profiling for blood cancer, solid tumors as well as general tumor profiling

Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), Solid Tumor, Tumours Profiling, MRC HOLLAND, Clinical Diagnostics

MLPA Probemixes for Cancer Predisposition

SALSA® MLPA® Probemixes for Cancer Predisposition are used for determining DNA copy number variations in individuals who have a genetic predisposition to various cancers, including breast, ovarian, colorectal, endometrial, gastric, and small bowel cancer, among others. MLPA Assay is a simple, robust and multiplex PCR-based assay.

Applications & Specialities, Early cancer detection, Genetic Disorders, MLPA, MLPA, Products & Services, MRC HOLLAND, Clinical Diagnostics

Testimonials & Reviews

Dr. Chhaya Chande, Professor & HOD, Microbiology
Dr. Chhaya Chande, Professor & HOD, Microbiology
GGMCJJ Hospitals, Mumbai

“Ms. Megha Dhumal (Assistant Manager- Application) has done a satisfactory demonstration of the running of the Abbott Sample preparation machine model m2000sp and the Abbott RT-PCR machine model m2000rt. We appreciate the effort made by the DSS team under these difficult conditions to help our lab to carry out the imperative Covid-19 tests.”

Dr Sunil K Arora, Professor, Deptt of Immunopathology
Dr Sunil K Arora, Professor, Deptt of Immunopathology
PGIMER, Chandigarh

“We are using Confocal Microscope and one Fluorescence Microscope. Both are working fine. The after sales services by DSS have been excellent for functioning & upkeep of the microscopes. The applications support by experts from DSS is very useful. Keep it up!”

Dr Pramod Kumar Bajaj
Dr Pramod Kumar Bajaj
MD, Spermprocessor Pvt Ltd

“Really excited to see the DSS Pathology solutions exhibition booth at APCON 2019 along with Magnus. We think all the upcoming technology had been displayed along with your efforts to make it Indigenous (Made in India) is highly appreciated. Wish you all the best. Keep it up!”

Dr. Sreejesh S, Associate Professor, Dept of Hematology
Dr. Sreejesh S, Associate Professor, Dept of Hematology
PGIMER, Chandigarh

“My experience with DSS so far has been very good till now. We are getting good support in both purchase as well as in troubleshooting. Very good experience with Mr Arun, Mr Manoj, Mr Mahesh and all others from the DSS team.”

Dr Sudha S Murthy, Department of Pathology and Laboratory Medicine
Dr Sudha S Murthy, Department of Pathology and Laboratory Medicine
BIACH & RI, Hyderabad

“I am happy with DSS and associated with 19 years and use Dako antibody. Happy with Supply but need improvement.”

Dr S Radhika MD, PhD
Dr S Radhika MD, PhD
Professor, Deptt. Of Cytology & Gynaec Pathology, PGIMER, Chandigarh

“PGI Cytology Dept. has had a long association with DSS- Olympus Microscopy Division. They have provided excellent services- after sales service. The product is also of very good quality. We have had no problems with their products and services are of very good quality.”

Dr Nuzhat Husain
Dr Nuzhat Husain
RMLIMS, Lucknow

“Have been using Dako Reagants and Dako antibodies for a while. Services and products have been good and timely.”

Dr Minu Singh
Dr Minu Singh
Assistant Professor, PGIMER, Chandigarh

“MRC Holland MLPA products provided by DSS are of good quality, have never faced any quality issues with their product or shipping condition. They provide prompt response upon any query.”

Mr. Krishnani
Mr. Krishnani Professor, SGPGI, Lucknow

“My experience with DSS so far has been excellent for the last 30 years- sales and service experience. Microscope products are very useful and sturdy with high precision.”