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Home > Oncology > Clonality
Clonality
Lymphoid cells are different from the other somatic cells in the body as during development, the antigen receptor genes in lymphoid cells undergo somatic gene arrangement. Leukemia & lymphomas originate from the malignant transformation of individual lymphoid cells. Therefore, all leukemias and lymphomas generally have one or more cell-specific or ‘clonal’ antigen receptor gene rearrangements. Clonality does not always imply malginancy; all results must be interpreted in the context of all other available indicative characteristics. IVS assays detect clonal rearrangements & can therefore prove to be useful in the characterization and treatment of B- and T-cell malignancies.


Clonality Based Testing (ABI Fluorescence Detection)
ABI Fluorescence Detection is done using ABI 310, 3100 & 3130 instruments.
Applications & Specialities, Clonality, Clonality in Lymphoprolifertive Processes, Fluorescence Microscopy, Molecular Pathology & Diagnostics, Invivoscribe, Clinical Diagnostics
Clonality Based Testing (Gel Detection)
Gel Detection is done using Agarose TBE Gels,Polyacrylamide TBE Gels,Heteroduplex Analysis
Applications & Specialities, Clonality, Clonality in Lymphoprolifertive Processes, Molecular Pathology & Diagnostics, Invivoscribe, Clinical Diagnostics
DNA/RNA Controls
Controls play a crucial role in invalidation. Invivoscribe provides controls manufactured in cGMP conditions.
Applications & Specialities, Clonality, Molecular Pathology & Diagnostics, Invivoscribe, Clinical Diagnostics
NGS Assays (Illumina Miseq)
The MiSeq helps in analysing clonal amplification, genomic DNA sequencing, and data analysis in a single run.
Applications & Specialities, Clonality, Molecular Pathology & Diagnostics, Sequencing, Invivoscribe
NGS Assays (Thermofisher Ion PGM™ or Ion S5™platforms)
Thermofisher's Ion PGM™ or Ion S5™platforms help in targeted gene sequencing in oncology and genetic disorders.
Applications & Specialities, Clonality, Molecular Pathology & Diagnostics, Sequencing, Invivoscribe, Clinical Diagnostics
Somatic Hypermutation (ABI Fluorescence Detection)
ABI Fluorescence Detection is done using ABI 310, 3100 & 3130 instruments.
Applications & Specialities, Clonality, Fluorescence Microscopy, Molecular Pathology & Diagnostics, Invivoscribe, Clinical Diagnostics
Somatic Hypermutation (Gel Detection)
Gel Detection is done using Agarose TBE Gels,Polyacrylamide TBE Gels,Heteroduplex Analysis
Applications & Specialities, Clonality, Molecular Pathology & Diagnostics, Invivoscribe, Clinical Diagnostics
Testimonials & Reviews



Dr. Chhaya Chande, Professor & HOD, Microbiology
GGMCJJ Hospitals, Mumbai
“Ms. Megha Dhumal (Assistant Manager- Application) has done a satisfactory demonstration of the running of the Abbott Sample preparation machine model m2000sp and the Abbott RT-PCR machine model m2000rt. We appreciate the effort made by the DSS team under these difficult conditions to help our lab to carry out the imperative Covid-19 tests.”

Dr Sunil K Arora, Professor, Deptt of Immunopathology
PGIMER, Chandigarh
“We are using Confocal Microscope and one Fluorescence Microscope. Both are working fine. The after sales services by DSS have been excellent for functioning & upkeep of the microscopes. The applications support by experts from DSS is very useful. Keep it up!”

Dr Pramod Kumar Bajaj
MD, Spermprocessor Pvt Ltd
“Really excited to see the DSS Pathology solutions exhibition booth at APCON 2019 along with Magnus. We think all the upcoming technology had been displayed along with your efforts to make it Indigenous (Made in India) is highly appreciated. Wish you all the best. Keep it up!”

Dr. Sreejesh S, Associate Professor, Dept of Hematology
PGIMER, Chandigarh
“My experience with DSS so far has been very good till now. We are getting good support in both purchase as well as in troubleshooting. Very good experience with Mr Arun, Mr Manoj, Mr Mahesh and all others from the DSS team.”

Dr Sudha S Murthy, Department of Pathology and Laboratory Medicine
BIACH & RI, Hyderabad
“I am happy with DSS and associated with 19 years and use Dako antibody. Happy with Supply but need improvement.”

Dr S Radhika MD, PhD
Professor, Deptt. Of Cytology & Gynaec Pathology, PGIMER, Chandigarh
“PGI Cytology Dept. has had a long association with DSS- Olympus Microscopy Division. They have provided excellent services- after sales service. The product is also of very good quality. We have had no problems with their products and services are of very good quality.”

Dr Nuzhat Husain
RMLIMS, Lucknow
“Have been using Dako Reagants and Dako antibodies for a while. Services and products have been good and timely.”

Dr Minu Singh
Assistant Professor, PGIMER, Chandigarh
“MRC Holland MLPA products provided by DSS are of good quality, have never faced any quality issues with their product or shipping condition. They provide prompt response upon any query.”

Mr. Krishnani Professor, SGPGI, Lucknow
“My experience with DSS so far has been excellent for the last 30 years- sales and service experience. Microscope products are very useful and sturdy with high precision.”
