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Genetic Disorders
Any kind of mutations in the gene can cause genetic disorders. Genetic Disorders are generally hereditary in nature. However, they can also occur due to lifestyle.
The most commonly found genetic disorders are:
1. Mutations in a Single Gene. e.g. Sickle Cell Anemia
2. Mutations in a Chromosome. e.g. Down Syndrome
3. Mutations in Multiple (Two or more) Genes e.g. Colon Cancer
DSS has multitude of solutions for genetic disorders from Abbott Molecular’s flagship Vysis FISH Probe – AneuVysion (for abnormalities 13, 18, 21, X & Y genes) to Melt Assays and other MLPA Probes (eg. DMD-1 / DMD-2) from MRC Holland.
Hyperspectral Karyotyping
GenASIs HiSKY performs Hyperspectral Karyotyping analysis, leveraging the benefits of multiplexed spectral imaging to obtain a karyotype which uniquely colors each chromosome and provides a level of detailed analysis not available with any other karyotyping technique.
Applications & Specialities, Cytogenetic Software, Flagship Products, Karyotyping, Software, APPLIED SPECTRAL IMAGING, Microscopy & Imaging
Lymphocyte Growth Supplement
Lymphocyte Growth Supplement is a ProCell Cytogenetics Reagent that is a complex mixture of growth promoters that have a marked stimulatory effect on peripheral lymphocyte cultures.
Applications & Specialities, Cytogenetic Solutions, Cytogenetics, Karyotyping, ProCell Cytogenetics Reagents, Genial Helix, Clinical Diagnostics
Metaphase Arresting Solution
MAS (Metaphase Arresting Solution) is a ProCell Cytogenetics Reagent that is a highly refined solution of colchicine/vinblastine sulphate in PBS, used to increase the percentage of metaphase cells for chromosomal studies.
Applications & Specialities, Cytogenetic Solutions, Cytogenetics, Karyotyping, ProCell Cytogenetics Reagents, Genial Helix, Clinical Diagnostics
Methylation-Specific MLPA Assays
Methylation-Specific (MS)-MLPA® is a variant of the MLPA technique, the gold standard in copy number determination. With MS-MLPA, it is possible to semi-quantitatively profile methylation for multiple targets simultaneously.
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics
MLPA Assays for Lung Disorders
MLPA Assays are useful in finding out those who have Lung Disorders
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics
MLPA Assays for Cardiovascular Disorders
MLPA can be used for the detection of deletions or duplications of certain genes involved in cardiovascular diseases.
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics
MLPA Assays for Endocrinological Disorders
MLPA Assays are useful in finding out those who have endocrinological diseases.
Applications & Specialities, MLPA, MLPA, MRC HOLLAND, Clinical Diagnostics
MLPA Assays for Hereditary Blood Disorders
MLPA Assays are useful in finding out those who have hereditary blood disorders.
Applications & Specialities, Congenital & Hereditary Disorders, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics
MLPA Assays for Intellectual Disability
MLPA Assays are useful in finding out those who have Intellectual Disability
Applications & Specialities, Genetic Disorders, Intellectual Disability, Intellectual property, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND, Clinical Diagnostics
MLPA Assays for Neuromuscular Disorders
MLPA Assays are useful in finding out those who have Neuromuscular Disorders
Applications & Specialities, MLPA, MLPA, MRC HOLLAND, Clinical Diagnostics
MLPA Assays for Skeletal & Connective Tissue
MLPA Assays are useful in finding out those who have Skeletal & Connective Tissue Disorders
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), MRC HOLLAND
MLPA Assays for Tumour Profiling
MLPA Assays are useful in tumor profiling for blood cancer, solid tumors as well as general tumor profiling
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Multiplex Ligation-Dependent Probe Amplification (MLPA), Solid Tumor, Tumours Profiling, MRC HOLLAND, Clinical Diagnostics
MLPA Probemixes for Cancer Predisposition
SALSA® MLPA® Probemixes for Cancer Predisposition are used for determining DNA copy number variations in individuals who have a genetic predisposition to various cancers, including breast, ovarian, colorectal, endometrial, gastric, and small bowel cancer, among others. MLPA Assay is a simple, robust and multiplex PCR-based assay.
Applications & Specialities, Early cancer detection, Genetic Disorders, MLPA, MLPA, Products & Services, MRC HOLLAND, Clinical Diagnostics
MLPA Probemixes for Congenital Disorders & Carrier Testing
SALSA® MLPA® Probemixes for Congenital Disorders & Carrier Testing are used for determining DNA copy number variations in inherited disorders such as Alpha-Thalassemia (P140 HBA) , Congenital Adrenal Hypoplasia (P050 CAH), Cystic Fibrosis (P091 CFTR), Duchenne Muscular Dystrophy (P034 DMD-1; P035 DMD-2) and Spinal Muscular Atrophy (P021 SMA; P060 SMA Carrier; P460 SMA (Silent) Carrier).
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Products & Services, MRC HOLLAND
MLPA Probemixes for Imprinting Disorders
SALSA® Methylation - Specific (MS) - MLPA® Probemixes for Imprinting Disorders are used for determining DNA copy number variations and methylation status associated with conditions like Prader-Willi Syndrome, Angelman Syndrome, Beckwith-Wiedemann and Russell-Silver Syndrome.
Applications & Specialities, Genetic Disorders, MLPA, MLPA, Products & Services, MRC HOLLAND, Clinical Diagnostics
Optimal Hypotonic Solution
Optimal Hypotonic Solution is a ProCell Cytogenetics Reagent which is developed for acute leukaemia bone marrow and tumour cells, also useful with problem blood and other problematic sample types.
Applications & Specialities, Cytogenetic Solutions, Cytogenetics, Karyotyping, ProCell Cytogenetics Reagents, Genial Helix, Clinical Diagnostics
Testimonials & Reviews
Dr. Chhaya Chande, Professor & HOD, Microbiology
GGMCJJ Hospitals, Mumbai
“Ms. Megha Dhumal (Assistant Manager- Application) has done a satisfactory demonstration of the running of the Abbott Sample preparation machine model m2000sp and the Abbott RT-PCR machine model m2000rt. We appreciate the effort made by the DSS team under these difficult conditions to help our lab to carry out the imperative Covid-19 tests.”
Dr Sunil K Arora, Professor, Deptt of Immunopathology
PGIMER, Chandigarh
“We are using Confocal Microscope and one Fluorescence Microscope. Both are working fine. The after sales services by DSS have been excellent for functioning & upkeep of the microscopes. The applications support by experts from DSS is very useful. Keep it up!”
Dr Pramod Kumar Bajaj
MD, Spermprocessor Pvt Ltd
“Really excited to see the DSS Pathology solutions exhibition booth at APCON 2019 along with Magnus. We think all the upcoming technology had been displayed along with your efforts to make it Indigenous (Made in India) is highly appreciated. Wish you all the best. Keep it up!”
Dr. Sreejesh S, Associate Professor, Dept of Hematology
PGIMER, Chandigarh
“My experience with DSS so far has been very good till now. We are getting good support in both purchase as well as in troubleshooting. Very good experience with Mr Arun, Mr Manoj, Mr Mahesh and all others from the DSS team.”
Dr Sudha S Murthy, Department of Pathology and Laboratory Medicine
BIACH & RI, Hyderabad
“I am happy with DSS and associated with 19 years and use Dako antibody. Happy with Supply but need improvement.”
Dr S Radhika MD, PhD
Professor, Deptt. Of Cytology & Gynaec Pathology, PGIMER, Chandigarh
“PGI Cytology Dept. has had a long association with DSS- Olympus Microscopy Division. They have provided excellent services- after sales service. The product is also of very good quality. We have had no problems with their products and services are of very good quality.”
Dr Nuzhat Husain
RMLIMS, Lucknow
“Have been using Dako Reagants and Dako antibodies for a while. Services and products have been good and timely.”
Dr Minu Singh
Assistant Professor, PGIMER, Chandigarh
“MRC Holland MLPA products provided by DSS are of good quality, have never faced any quality issues with their product or shipping condition. They provide prompt response upon any query.”
Mr. Krishnani Professor, SGPGI, Lucknow
“My experience with DSS so far has been excellent for the last 30 years- sales and service experience. Microscope products are very useful and sturdy with high precision.”
