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S@femate Cyto – Class II MicroBiological Safety Cabinets
Cytotoxic drugs are therapeutic agents intended for, but not limited to, the treatment of cancer. These drugs are known to be highly toxic to cells, mainly through their action on cell reproduction. Many have proved to be carcinogens, mutagens or teratogens. Cytotoxic drugs are increasingly being used in a variety of healthcare settings, laboratories and veterinary clinics for the treatment of cancer and other medical conditions such as rheumatoid arthritis, multiple sclerosis and auto-immune disorders. Health effects attributed to exposure to occupational cytotoxic drugs can be very serious. Research shows that where a high standard of risk control is in place, threats to healthcare are reduced.
No exposure limits are set for cytotoxic drugs. Medical opinion is such that even low-level exposure to cytotoxic drugs should be avoided as much as possible. Research has shown that the implementation of suitable safety precautions reduces the incidence of adverse health effects. EuroClone cytotoxic drugs handling Cabinet S@femate® Cyto, has been designed according to DIN12980 and EN12469:2000 standards and provides the laboratory technician with the maximum level of safety against inhalation of aerosols generated during the reconstitution protocols.
These last generation Cytotoxic drug handling Cabinets have been designed according with the most stringent safety standards for this category of Safety Cabinets (DIN12980, EN12469). The internal design, the air flow aerodynamics and monitoring, the built-in safety devices and the very accurate manufacturing, guarantees the highest performances at the most stringent safety levels, as specified by DIN 12980 and EN12469. Intrinsic safety, combined with impressively competitive prices, gives the end user a state of the art cabinet accessible to every budget, that only experienced European design and accurate quality manufacturing, can provide.
Other than the two classic H14 filters needed for the filtration of exhausted air and downflow recirculating unidirectional airflow, a tertiary filtration stage (with bag-in bag-out filter changing protocol according to KTA 3601 Lüftungstechnische Anlagen in Kernkraftwerken) is located underneath the work surface in order to provide, by filtering 100% of the recirculated airflow, the required safety for the maintenance personnel when removing this stage of filtration for substitution
Four levels of safety are therefore provided:
- Safety for the operator, (extremely high Aperture protection factor) identical to the one provided by a Biological Safety Cabinet
- Safety for the environment (double H14 filtration stage in the exhaust)
- Safety for the product and between products (class 100 in the work area)
- Safety for the engineers when changing the tertiary filter stage (bag-in bag-out procedure)
Features and Benefits
- Microprocessor controlled motor blower, with volumetric sensor for exhausted air flow monitoring
- Volt-free contact for remote monitoring of exhaust fan.
- Automatic reset of initial conditions in case of power failure.
- Sloped front design for the highest operational comfort. Sloped back side of the working chamber for the best down flow distribution.
- Utilities inlets from the top of the cabinet.
- Stainless Steel internal surfaces with 2B finishing (including spillage tray). Solid work surface (2 sections) and special designed front grill.
- Electrically operated sliding multilayer safety glass window (max opening at 120)
- Comfortable 195 mm front opening
- Exposed exhaust Hepa filter for easy visual integrity check.
- Three stages of H14 class High Efficiency Particulate Air filters with > 99. 995% efficiency on 0.1 - 0.2 micron particles (MPPS) (EN1822-1)
- Filter change and maintenance from the front of the cabinet for all stage of filters.
- Bag-in bag-out tertiary filter stage changing technology (avoiding ruptrue of isolation continuity of the work area during filter changing)
- Exhaust transitions easily installable.
About
BioAir, an Italian leader in contamination control equipment, caters to the needs of biomedical research and biopharmaceutical production. In 2021, BioAir joined the Tecniplast group, a global frontrunner in laboratory animal science equipment. BioAir provides a comprehensive suite of laboratory solutions, combining BioAir’s expertise in contamination control with Labosystem's laboratory furnishings and KW’s temperature-controlled equipment. This unified approach offers clients an extensive and seamless laboratory experience. DSS Imagetech is committed to advancing laboratory technology and providing high-quality solutions for scientific research. BioAir, part of the renowned Tecniplast family, enables us to offer a robust selection of contamination control equipment ideal for cutting-edge biomedical research. DSS Imagetech and BioAir aim to redefine laboratory standards, enhancing research efficiency and safety across diverse scientific fields and biopharmaceutical production.
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Dr S Radhika MD, PhD
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Assistant Professor, PGIMER, Chandigarh
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Mr. Krishnani Professor, SGPGI, Lucknow
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